Lysosomes are membrane bound organelles found in eucaryotic cells. They contain digestive enzymes, responsible for the degradation of proteins sent here.

This is the signal to sort proteins into multivesicular bodies, thus targetting them for degradation. The process is a post translational modification, and is carried out by ubiquitin ligases. It involves the covalent attachment of highly conserved ubiquitin proteins to the lysines of other...

Multivesicular bodies form from the inward budding of the endosomal membrane. These fuse with one an aother to form the late endosome.

This is the internalisation of large particles- micro-organsims, dead cells etc. through large vesicles called phagosomes.  Protozoa use phagocytosis as a form of feeding. In most animals, cells including macrophages act as phagocytes ingesting invading micro-organsims, thus acting as a...

PI3P = phosphatidylinositol(3)-phosphate PI3P is a marker of the early endosome. Proteins which are able to bind to PI3P can thus be recruited to the early endosome.

Pinocytosis is often referred to as "cellular drinking". This is the internalisation of small molecules-fluid, solutes, parts of the plasma membrane etc through small pinocytic vesicles. Pinocytic vesicles are also called endocytic vesicles.

The process where materials are moved across the cell. This can be in an apical to basolateral direction, or a basolateral to apical direction.

Clathrin triskelions are the subunits which come together to form clathrin coated pits. Each triskelion is composed of three clathrin heavy chains and three clathrin light chains.